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Linoleic acid-13C18 is a 13C labeled version of Linoleic acid. Linoleic acid is a common polyunsaturated fatty acid (PUFA) found in plant-based oils, nuts, and seeds. It is a component of membrane phospholipids, providing structural support to maintain membrane fluidity in the transdermal water barrier of the epidermis. Linoleic acid can cause damage to red blood cells and hemoglobin through an oxidative mechanism.
Used as a tracer.
Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Stable heavy isotopes of carbon have been incorporated into the molecule.
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Aphidicolin is an inhibitor of DNA polymerase α and δ, preventing mitotic cell division by interfering with DNA polymerase activity. It is an antibiotic produced by the mold *Cephalosporium aphidicola*, inhibiting cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin also exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.
Inhibits DNA polymerase α and δ
Prevents mitotic cell division
Interferes with DNA polymerase activity
Antibiotic produced by *Cephalosporium aphidicola*
Inhibits cellular deoxyribonucleic acid synthesis
Inhibits growth of herpes simplex virus
Exhibits anti-orthopoxvirus activity
Potentiates apoptosis induced by arabinosyl nucleosides
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Betaine-d9 (chloride) is the deuterium labeled Betaine chloride. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Paclitaxel is a microtubule polymer stabilizer with IC50 of 0 1 pM in human endothelial cells Paclitaxel can cause both mitotic arrest and apoptotic cell death Paclitaxel also induces autophagy
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Lissamine Fast Red solution is a prepared, ready-to-use, high quality staining solution that saves time and effort and produces consistent uniform results.
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